Abstract:Exosomes, as endogenous Nano-vesicles, contain important genetic information and functional molecules, which play an important role in signal transmission between cells. Exosomes can pass through the bloodbrain barrier and establish communication between peripheral circulation and the central nervous system, which makes them the potential biomarkers and novel remedies for nervous system diseases. Traumatic brain injury (TBI) is one of the leading causes of death and disability of patients at all ages. Its diagnosis and treatment are still full of challenges. The authors summarize the biological characteristics of exosomes and the research progress in exosomes for diagnosis and treatment of TBI, so as to provide new ideas for the study of TBI.
宋煜 董艳 高亮. 外泌体对创伤性脑损伤诊治作用的研究进展[J]. 中华创伤杂志, 2020, 36(7): 664-669.
Song Yu, Dong Yan, Gao Liang.. Research progress in exosomes for diagnosis and treatment of traumatic brain injury. CHINESE JOURNAL OF TRAUMA, 2020, 36(7): 664-669.