Abstract:Objective To investigate the factors affecting the outcome of surgical treatment for femoral intertrochanteric fractures. Methods A retrospective case series study was conducted for 424 patients with intertrochanteric fractures admitted to four hospitals in Shanghai from January 2014 to December 2016. There were 200 males and 224 females, aged 45-98 years [(77.8±10.5)years]. Normal union was observed in 326 patients (normal union group), and abnormal union was founded in 98 patients including nonunion in 2 patients (abnormal union group). Data were recorded including the age, gender, injury side, AO classification, Evans-Jesen classification, thickness of femoral lateral wall, medial support, tip-apex distance, and screw position within the femoral head. Fracture healing was assessed. Univariate analysis was conducted to examine differences of the above factors between two groups, and Logistic regression was used to screen the main factors affecting fracture union. At the latest follow-up, the hip joint function was estimated according to the Oxford score system. Results All patients were followed up for 1-3 years [(2.2±0.3)years]. Univariate analysis showed significant differences between two groups regarding the AO classification, Evans-Jesen classification, medial support, tip-apex distance, and screw position within the femoral head (P<0.05). Multivariate regression analysis revealed that the simple fracture (OR=1.030), medial support (OR=0.395), tip-apex distance ≤25 mm (OR=0.266) and inferior screw position (OR=0.986) were significantly related to fracture union. The hip function in normal union group was (42.6±4.5)points, better than (35.4±3.2)points in abnormal union group (P<0.05). Conclusion The stability of intertrochanteric fracture is the most important factor for fracture union. The medial support, tipapex distance ≤25 mm and inferior screw position are helpful to promote fracture healing and recovery of hip joint function.