Objective To evaluate the effect of laparoscopic sandwich repair technique in spleen salvage for patients with high-grade blunt splenic trauma.Methods A retrospective study was performed in 24 patients with high-grade blunt splenic trauma undergone sandwich repair laparoscopically for hemostasis and spleen preservation after the failed non-operative therapy.Surgical techniques,surgical outcomes,postoperative recovery,and follow-up results were evaluated.Results Of all,21 patients (88%) underwent laparoscopic sandwich repair for hemostasis and spleen preservation successfully; 2 were converted to the laparoscopic splenectomy due to complex splenic rupture; 1 was converted to an open splenectomy due to unstable hemodynamics.Mean time to reach hemostasis was (36.7 ± 22.0) minutes and operation time was (136.3 ±40.3) minutes; mean blood loss was (1 598.0 ±940.0) ml and length of hospital stay was (10.8 ± 5.4) days.All patients were recovered at discharge.There were no complications of re-bleeding,total splenic infarction,or abdominal abscess at the 3-month follow-up.Conclusion Laparoscopic sandwich repair technique can be used effectively for spleen salvage in patients with high-grade splenic trauma.