Abstract：Objective To mneasure the effect of percutaneous vertebroplasty (PVP) in treatment of severe osteoporotic vertebral compression fractures.Methods A retrospective study was performed on 25 patients with severe osteoporotic vertebral compression fractures undergone PVP under local anesthesia after no obvious evidence of contraindication was detected.There were nine males and sixteen females,at a mean age of 71.3 years (range,65-87 years).All the patients sustained a history of fourmonth of severe lumbar and back pain.Radiograph and MRI confirmed the diagnosis of osteoporotic vertebral compression fractures,with average (72.4 ± 11.3) ％ compression of the affected vertebral body.Chest-back pain was assessed by visual analogue scale (VAS).Results All operations succeeded without any harmful complications.Mean bone cement injected to each injured vertebral body was 2.7 ml(range,2-4 ml).Complete relief in lumbar and back pain was achieved in seven patients,remarkable relief in 14 patients,and some improvement in four patients.At the follow-up of mean 13.1 months (range,6-24 months),VAS improved from (7.51 ± 1.62) points preoperatively to (2.45 ± 1.34)points postoperatively (P ＜ 0.01).Conclusion PVP ameliorates significantly the symptoms associated with severe osteoporotic vertebral compression fractures in the elderly,reduces complications and improves patients' quality of life.
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